Muramidase, α-1 antitrypsin, α-1 antichymotrypsin, and S-100 protein immunoreactivity in giant cell lesions

α1-Antichymotrypsin/Alzheimer's peptide

α1-Antichymotrypsin/Alzheimer's peptide Aβ1–42 complex perturbs lipid metabolism and activates transcription factors PPARγ and NFκB in human neuroblastoma (Kelly) cells

✍ Yong-Xin Sun; H.T. Wright; S. Janciauskiene 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 948 KB

Amyloid-beta peptide (A␤) and the serpin proteinase inhibitor ␣1-antichymotrypsin (ACT) are components of the amyloid plaques associated with Alzheimer's disease (AD). A␤ exists in soluble monomeric and oligomeric forms and in an insoluble polymerised fibrillar form, but it is not clear which of the