𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Multkilogram Scale-Up of a Reductive Alkylation Route to a Novel PARP Inhibitor

✍ Scribed by Gillmore, Adam T.; Badland, Matthew; Crook, Clare L.; Castro, Nieves M.; Critcher, Douglas J.; Fussell, Steven J.; Jones, Katherine J.; Jones, Matthew C.; Kougoulos, Eleftherios; Mathew, Jinu S.; McMillan, Lynne; Pearce, John E.; Rawlinson, Fiona L.; Sherlock, Alexandra E.; Walton, Robert


Book ID
118042421
Publisher
American Chemical Society
Year
2012
Tongue
English
Weight
386 KB
Volume
16
Category
Article
ISSN
1083-6160

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Reductive alkylation of urea: A practica
✍ Daqiang Xu; Lech Ciszewski; Tangqing Li; Olijan Repič; Thomas J. Blacklock πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 188 KB

Conditions are disclosed for the formation of either mono-or di-substituted ureas by reductive alkylation, which are :readily adaptable to large scale preparations. Dehydrating agents such as acetyl chloride or Iximethylsilyl chloride effectively