✦ LIBER ✦

Multivariate quantitative structure–pharmacokinetic relationships (QSPKR) analysis of adenosine A1 receptor agonists in rat

✍ Scribed by Pieter H. van der Graaf; Jonas Nilsson; Erno A. van Schaick; Meindert Danhof

Book ID: 109389165
Publisher: John Wiley and Sons
Year: 1999
Tongue: English
Weight: 125 KB
Volume: 88
Category: Article
ISSN: 0022-3549
DOI: 10.1021/js980294a

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Blood–brain barrier transport of synthet

Blood–brain barrier transport of synthetic adenosine A1 receptor agonists in vitro: structure transport relationships

✍ Marloes P Schaddelee; Heleen L Voorwinden; Dorien Groenendaal; Anne Hersey; Adri 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 151 KB

Quantitative structure–pharmacokinetic p

Quantitative structure–pharmacokinetic parameters relationships (QSPKR) analysis of antimicrobial agents in humans using simulated annealing k-nearest-neighbor and partial least-square analysis methods

✍ Chee Ng; Yunde Xiao; Wendy Putnam; Bert Lum; Alexander Tropsha 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

We have developed quantitative structure-pharmacokinetic parameters relationship (QSPKR) models using k-nearest-neighbor (k-NN) and partial least-square (PLS) methods to predict the volume of distribution at steady state (Vss) and clearance (CL) of 44 antimicrobial agents in humans. The performance

Species differences in structure-activit

Species differences in structure-activity relationships of adenosine agonists and xanthine antagonists at brain A1 adenosine receptors

✍ Dieter Ukena; Kenneth A. Jacobson; William L. Padgett; Cristina Ayala; Mah T. Sh 📂 Article 📅 1986 🏛 Elsevier Science 🌐 English ⚖ 627 KB

Pharmacokinetics and cardiovascular phar

Pharmacokinetics and cardiovascular pharmaco-dynamics in rats of three adenosine A1-receptor agonists with differing lipophilicity

✍ E.A. van Schaick; G. Cristalli; A.P. Ijzerman; M. Danhof 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 160 KB

Adenosine A1 and non-A1 receptors: Intra

Adenosine A1 and non-A1 receptors: Intracellular analysis of the actions of adenosine agonists and antagonists in rat hippocampal neurones

✍ Angela Ameri; Ilmar Jurna 📂 Article 📅 1991 🏛 Elsevier Science 🌐 English ⚖ 881 KB

Pharmacokinetic-pharmacodynamic modellin

Pharmacokinetic-pharmacodynamic modelling of the anti-lipolytic and anti-ketotic effects of the adenosine A1-receptor agonist N6-(p-sulphophenyl)adenosine in rats

✍ E. A. Van Schaick; H. J. M. M. de Greef; M. W. E. Langemeijer; M. J. Sheehan; A. 📂 Article 📅 1997 🏛 Nature Publishing Group 🌐 English ⚖ 432 KB