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Multivalent iminosugars to modulate affinity and selectivity for glycosidases

✍ Scribed by Diot, Jennifer ;García-Moreno, M. Isabel ;Gouin, Sébastien G. ;Ortiz Mellet, Carmen ;Haupt, Karsten ;Kovensky, José


Book ID
118262302
Publisher
Royal Society of Chemistry
Year
2009
Tongue
English
Weight
221 KB
Volume
7
Category
Article
ISSN
1477-0520

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## Abstract A set of engineered peptides (33 amino acids long) corresponding to the helix‐turn‐helix (EF‐Hand) motif of the metal‐binding site I of the protein calmodulin from __paramecium tetraurelia__ have been synthesized. A disulfide bridge has been introduced in the native sequence in order to