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Multistate approaches in computational protein design

โœ Scribed by James A. Davey; Roberto A. Chica


Book ID
115561340
Publisher
Cold Spring Harbor Laboratory Press
Year
2012
Tongue
English
Weight
550 KB
Volume
21
Category
Article
ISSN
0961-8368

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## Abstract Multistate protein design is the task of predicting the amino acid sequence that is best suited to selectively and stably fold to one state out of a set of competing structures. Computationally, it entails solving a challenging optimization problem. Therefore, notwithstanding the increa