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Multiscale Ensemble Modeling of Intrinsically Disordered Proteins: p53 N-Terminal Domain

✍ Scribed by Terakawa, Tsuyoshi; Takada, Shoji


Book ID
119209086
Publisher
Biophysical Society
Year
2011
Tongue
English
Weight
820 KB
Volume
101
Category
Article
ISSN
0006-3495

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## Abstract It is known that the half life of the tumor suppressor p53 can be increased by the interaction with the bacterial protein azurin, resulting in an enhanced anti‐tumoral activity. The understanding of the molecular mechanisms on the basis of this phenomenon can open the way to new anti‐ca