✦ LIBER ✦

Multipotent progenitor cells in the adult dentate gyrus

✍ Scribed by Gage, Fred H. ;Kempermann, Gerd ;Palmer, Theo D. ;Peterson, Daniel A. ;Ray, Jasodhara

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Volume: 36
Category: Article
ISSN: 0022-3034
DOI: 10.1002/(sici)1097-4695(199808)36:2<249::aid-neu11>3.0.co;2-9

No coin nor oath required. For personal study only.

✦ Synopsis

Neurogenesis persists in the adult dentate gyrus of rodents throughout the life of the organism. The factors regulating proliferation, survival, migration, and differentiation of neuronal progenitors are now being elucidated. Cells from the adult hippocampus can be propagated, cloned in vitro, and induced to differentiate into neurons and glial cells. Cells cultured from the adult rodent hippocampus can be genetically marked and transplanted back to the adult brain, where they survive and differentiate into mature neurons and glial cells. Although multipotent stem cells exist in the adult rodent dentate gyrus, their biological significance remains elusive.

📜 SIMILAR VOLUMES

Impaired survival of neural progenitor c

Impaired survival of neural progenitor cells in dentate gyrus of adult mice lacking FMRP

✍ Orly Lazarov; Michael P. Demars; Kai Da Tommy Zhao; Haroon M. Ali; Vanessa Grauz 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 249 KB

## Abstract Fragile X syndrome (FXS) is the most common form of inherited intellectual disability in humans. Individuals affected with the disorder exhibit a deficiency of the fragile X mental retardation protein (FMRP), due to transcriptional silencing of the __Fmr1__ gene. It is widely accepted t

Proliferative status of cells in adult h

Proliferative status of cells in adult human dentate gyrus

✍ Del Bigio, Marc R. 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 203 KB

Experiments in rodents and marmoset monkeys indicate that granule neurons of the dentate gyrus may be renewable throughout the entire life of the animal. Whether this occurs in larger primates remains a matter of contention. However, a recent study of brain samples from five adult humans who had bee

GABAergic signaling in young granule cel

GABAergic signaling in young granule cells in the adult rat and mouse dentate gyrus

✍ Yashmin J.G. Karten; Meredith A. Jones; Sara I. Jeurling; Heather A. Cameron 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 410 KB 👁 1 views

## Abstract Throughout most of the developing brain, including the hippocampus, GABAergic synapses are the first to become functional. Several features of GABAergic signaling change across development, suggesting that this signaling in the immature brain may play important roles in the growth of yo

Adult neurogenesis produces a large pool

Adult neurogenesis produces a large pool of new granule cells in the dentate gyrus

✍ Heather A. Cameron; Ronald D.G. Mckay 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 1 views

Functional differentiation of ganglion c

Functional differentiation of ganglion cells from multipotent progenitor cells in sliced retina of adult goldfish

✍ Tamalu, F.; Chiba, C.; Ishida, A.T.; Saito, T. 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 245 KB 👁 2 views

Multipotent progenitor cells at the retinal margin of adult goldfish give rise to all cell types in the rest of the retina. We took advantage of this spatial arrangement of progenitor and mature cells in slices of peripheral retina, to investigate the appearance and maturation of voltageactivated Na

Progenitor cells in the adult pancreas

✍ Andrew M. Holland; L. Jorge Góñez; Leonard C. Harrison 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 270 KB