Multipoint analysis of chromosome 11p markers
β Scribed by David E. Goldgar; Pamela R. Fain
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 308 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0741-0395
No coin nor oath required. For personal study only.
β¦ Synopsis
and Boys Tuwn National Institute, Omaha, N e b r a s k a 68131 (P.R.F.)
The nature of the problems posed for the l l p segment of the fourth Genetic Analysis Workshop w e r e discussed in some detail i n the summary paper, as w e r e the characteristics of the two
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## Abstract Variance component models form a powerful and flexible tool for multipoint linkage analysis of quantitative traits. Estimates of genetic similarity are needed for the variance component model to detect linkage and to locate genes, and two methods are commonly used to calculate multipoin
## Abstract Multipoint linkage methods are powerful tools that are often employed as the first means to discover alleles affecting liability to diseases. With the advent of dense marker maps, linkage disequilibrium (LD) between markers is inevitable and it comes at the cost of bias and an increased