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Multiplex Amplicon Quantification (MAQ), a fast and efficient method for the simultaneous detection of copy number alterations in neuroblastoma

✍ Scribed by Candy Kumps; Nadine Van Roy; Lien Heyrman; Dirk Goossens; Jurgen Del-Favero; Rosa Noguera; Jo Vandesompele; Frank Speleman; Katleen De Preter

Book ID
115003297
Publisher
BioMed Central
Year
2010
Tongue
English
Weight
393 KB
Volume
11
Category
Article
ISSN
1471-2164

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## Abstract Recent genomic studies have shown that copy number abnormalities (CNA) of genes involved in lymphoid differentiation and cell cycle control are common in B‐cell precursor acute lymphoblastic leukemia (BCP‐ALL). We have evaluated Multiplex Ligation‐dependent Probe Amplification (MLPA) on