Multiple-spectrometer software

• Publisher: Elsevier Science
• Year: 2005
• Tongue: English
• Weight: 236 KB
• Volume: 8
• Category: Article
• ISSN: 1369-7021
• DOI: 10.1016/s1369-7021(05)71252-9

✦ Synopsis

TOOLS & TECHNIQUES UPDATE Positioner scales height

Mad City Labs' Nano-Z500 piezodriven nanopositioner allows high-throughput single-cell fluorescence microscopy and fast, high-resolution confocal imaging while adjusting z-axis height to remove effects of multiwell plate irregularities. Flexure-guided motion and internal sensors provide closed-loop positioning resolution of <3 nm over the 500 µm travel range. A 15 ms step response allows the z-section to be acquired quickly with minimal photobleaching. Multiframe images of kinetic events can be recorded in fractions of a second. Using the Nano-Drive™ controller, commands may be analog or digital.