Multiple signalling pathways mediate insulin-stimulated gene expression in 3T3-L1 adipocytes
✍ Scribed by Ainsley A Culbert; Jeremy M Tavaré
- Book ID
- 114147623
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 234 KB
- Volume
- 1578
- Category
- Article
- ISSN
- 0167-4781
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## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas
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