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Multiple signaling events in amyloid β-induced, oxidative stress-dependent neuronal apoptosis

✍ Scribed by Elena Tamagno; Maurizio Parola; Michela Guglielmotto; Gianni Santoro; Paola Bardini; Laura Marra; Massimo Tabaton; Oliviero Danni

Book ID
114275589
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
864 KB
Volume
35
Category
Article
ISSN
0891-5849

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## Abstract β‐amyloid peptide (Aβ) has been implicated in the pathogenesis of Alzheimer disease and has been reported to induce apoptotic death in cell culture. Cysteine proteases, a family of enzymes known as caspases, mediate cell death in many models of apoptosis. Multiple caspases have been imp