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Multiple sclerosis and HLA: Is the susceptibility gene really HLA-DR or -DQ?

✍ Scribed by Francis, D.A.; Thompson, A.J.; Brookes, P.; Davey, N.; Lechler, R.I.; McDonald, W.I.; Batchelor, J.R.


Book ID
121778410
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
360 KB
Volume
32
Category
Article
ISSN
0198-8859

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Multiple sclerosis and HLA class II susc
✍ Dr. D. G. Haegert; M. Michaud; C. Schwab; G. S. Francis πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 826 KB

Probes to the HLA class I1 genes DRP, DQP, and DQa were used to study DNA from unrelated Caucasian multiple sclerosis (MS) patients by sequential restriction fragment length polymorphism (RFLP) analysis in Taql restriction enzyme digests. Comparison of 104 patients and 108 controls, who were not mat