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Multiple regions of chromosome 16q demonstrating LOH in hepatocellular carcinomas

โœ Scribed by J. Sheu; Y. Lin; Y. Lee; C. Chen; H. Lee; G. Huang; P. Lee; F. Lu


Book ID
119527188
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
308 KB
Volume
34
Category
Article
ISSN
0168-8278

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Hepatocellular carcinoma (HCC) frequently shows a loss of heterozygosity (LOH) on chromosome 4q. In order to define the commonly affected region on chromosome 4q for further positional cloning of the putative tumor suppressor gene, we carried out allelic imbalance (AI) studies in 41 HCCs using a pan