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Multiple physical differences in the genome structure of functionally related bacteriophages P1 and P7

✍ Scribed by Iida, Shigeru ;Arber, Werner

Publisher
Springer
Year
1979
Tongue
English
Weight
968 KB
Volume
173
Category
Article
ISSN
0026-8925

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✦ Synopsis

Comparative restriction cleavage analysis of the genomes of bacteriophage P7, of several recombinant phages between P7 and P1, and of bacteriophage P1 allowed to draw PstI, Bg/II, BamHI and HindIII cleavage maps of all genomes studied. The data obtained complement Yun and Vapnek's (1977) conclusions with regard to areas of major nonhomology based on electron microscopical heteroduplex analysis and they identify several additional minor differences between P1 and P7. The use of hybrid phage strains allowed to locate the genes for particular functions on the physical genome map.

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