Multiple organ failure during interleukin-2 administration and LAK cells infusion

✍ Scribed by J. P. Sculier; D. Bron; J. Verboven; J. Klastersky

• Book ID: 104686647
• Publisher: Springer
• Year: 1988
• Tongue: English
• Weight: 185 KB
• Volume: 14
• Category: Article
• ISSN: 1432-1238
• DOI: 10.1007/bf00256776

✦ Synopsis

Adoptive immunotherapy is a new promising treatment for cancer but is associated with severe toxicity mainly related to a capillary leak syndrome. We report the case of a patient with metastatic hypernephroma, who had many complications such as coma, renal failure, pulmonary edema, life-threatening acidosis, cardiac arrhythmias and venous thrombosis. Critical care specialists should be aware of this type of cancer therapy because of multiple side effects requiring ICU supportive care.