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Multiple natural killer cell-activating signals are inhibited by major histocompatibility complex class I expression in target cells

✍ Scribed by Isabel Correa; Laura Corral; David H. Raulet


Publisher
John Wiley and Sons
Year
1994
Tongue
English
Weight
948 KB
Volume
24
Category
Article
ISSN
0014-2980

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Among tumor-infiltrating lymphocytes (TILs) directly isolated from renal cell carcinomas (RCCs), we found substantial numbers of natural killer (NK) cells in most tumor tissues. They could be identified reliably in situ with an antibody directed against the activating receptor (AR) NKp46 that is exc