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Multiple myeloma vaccine exhibits potent antitumour activity in murine models


Book ID
120865632
Publisher
Adis International Limited (now part of Wolters Kluwer Health)
Year
2001
Weight
133 KB
Volume
&NA;
Category
Article
ISSN
1173-8324

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A small molecule, LLL12 inhibits constit
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## Abstract We characterized the effects of a newly developed signal transducers and activators of transcription 3 (STAT3) inhibitor, LLL12 in multiple myeloma (MM) cells. LLL12 specifically inhibited STAT3 phosphorylation, nuclear localization, DNA binding activity, down‐regulated STAT3 downstream