Multiple myeloma: The biology of malignant plasma cells
โ Scribed by H.F. Barker; J. Ball; M. Drew; I.M. Franklin
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 702 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0268-960X
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Multiple myeloma (MM) is a clonal B-cell malignancy characterized by the aberrant expansion of plasma cells within the bone marrow, as well as at extramedullary sites. Decades of scientific research are now beginning to unravel the intricate biology that underlies the pathophysiology of MM. In parti
## Abstract Natural killer (NK) cells are cytotoxic lymphocytes able to kill tumor cells and virusโinfected cells. Humanโresting NK cells can be activated by coโculture with NKโresistant CTVโ1a cells. These tumorโactivated cells (TaNKs) are cytotoxic to a range of NKโresistant tumor cells in vitro.