Different genetic pathways to proximal a
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Jarle Breivik; Ragnhild A. Lothe; Gunn Iren Meling; Torleiv O. Rognum; Anne-Lise
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Article
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1997
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John Wiley and Sons
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French
β 322 KB
Mutations in the k-ras and TP53 genes, as well as microsatellite instability (MIN), are frequent genetic alterations in colorectal carcinomas and represent 3 different mechanisms in the carcinogenic process. Both the incidence of colorectal cancer and the frequency of genetic alterations in such tum