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Multiple doses of intravenous interleukin 10 in steroid-refractory Crohn's disease. Crohn's Disease Study Group

✍ Scribed by SJ van Deventer; CO Elson; RN Fedorak

Book ID
119755749
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
265 KB
Volume
113
Category
Article
ISSN
0016-5085

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Apoptosis resistance of mucosal lymphocy
Apoptosis resistance of mucosal lymphocytes and IL-10 deficiency in patients with steroid-refractory Crohn's disease
✍ Rebeca Santaolalla; Josep MaΓ±Γ©; Elisabet Pedrosa; Violeta LorΓ©n; Fernando FernΓ‘n πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 644 KB

Background: Apoptosis resistance of T-cells is considered an abnormality of immune pathways in Crohn's disease (CD). It has been previously shown that corticosteroids induce apoptosis of cells involved in inflammation. Thus, our aim was to assess the apoptosis of mononuclear cells and pro/antiinflam