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Multiple defects of the respiratory chain including complex II in a family with myopathy and encephalopathy

✍ Scribed by C. Desnuelle; M. Birch-Machin; J.F. Pellissier; L.A. Bindoff; B.A.C. Ackrell; D.M. Turnbull


Book ID
115762288
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
924 KB
Volume
163
Category
Article
ISSN
0006-291X

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Partial deficiency of complexes I and IV
✍ J. Bleistein; S. Zierz πŸ“‚ Article πŸ“… 1989 πŸ› Springer 🌐 English βš– 896 KB

Respiratory chain enzymes were studied in isolated mitochondria of two patients with mitochondrial myopathy. Both patients had been suffering from chronic progressive external ophthalmoplegia and abnormal muscular fatigability since late childhood. One of the patients exhibited the complete triad of