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Multiple Controls in Inflammation: Extracellular and Intracellular Phospholipase A2, Inducible and Constitutive Cyclooxygenase, and Inducible Nitric Oxide Synthase

✍ Scribed by Giuseppe Cirino

Book ID
119407351
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
311 KB
Volume
55
Category
Article
ISSN
0006-2952

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## Abstract The present study underlines the importance of phospholipase A~2~ (PLA~2~)‐ and lipoxygenase (LO)‐mediated signaling processes in the regulation of inducible nitric oxide synthase (iNOS) gene expression. In glial cells, lipopolysaccharide (LPS) induced the activities of PLA~2~ (calcium‐