Multiple conformational equilibria of cyclic octapeptide, cyclo (L-Pro-Sar)4 in solution
β Scribed by SHIMIZU, TOSHIMI ;TANAKA, YOSHIO ;TSUDA, KEISHIRO
- Book ID
- 115097969
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 2009
- Tongue
- English
- Weight
- 504 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0367-8377
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π SIMILAR VOLUMES
Cyclic octapeptides, cyclo(X-Pro)4, where X represents Phe, Leu, or Lys(Z), were synthesized and their conformations investigated. A Cz-symmetric conformer containing two cis peptide bonds was found in all of these cyclic octapeptides. The numbers of available conformations due to the cis-trans isom
## Abstract The crystal structure and conformation of the synthetic cyclic tetrapeptide, __cyclo__(LβProβSar)~2~, was determined by xβray analysis. The peptide crystallizes in the orthorhombic space group __P__2~1~2~1~2~1~ with cell parameters __a__ = 9.277(1), __b__ = 12.884(1), and __c__ = 15.581