The tumor promoter phorbol 13-myristate 12-acetate (PMA), the best characterized protein kinase C agonist, frequently regulates gene expression via activation of Fos/Jun (AP-1) complexes. PMA rapidly and transiently induces prostaglandin G/H synthase-2 (PGHS-2) expression in murine osteoblastic MC3T
β¦ LIBER β¦
Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters
β Scribed by Chiu, Robert; Imagawa, Masayoshi; Imbra, Richard J.; Bockoven, John R.; Karin, Michael
- Book ID
- 109750846
- Publisher
- Nature Publishing Group
- Year
- 1987
- Tongue
- English
- Weight
- 745 KB
- Volume
- 329
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/329648a0
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