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Multiple buoyant densities of hepatitis A virus in cesium chloride gradients

✍ Scribed by Dr. Daniel W. Bradley; Karen A. McCaustland; Marshall T. Schreeder; E. H. Cook; Clifton R. Gravelle; James E. Maynard

Publisher: John Wiley and Sons
Year: 1977
Tongue: English
Weight: 480 KB
Volume: 1
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890010309

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Hepatitis A virus (HAV) recovered from stools of human cases of hepatitis A and from stools of chimpanzees experimentally infected with HAV was shown to possess multiple buoyant densities in CsCl gradients. The greatest proportion of HAV was most frequently found at a buoyant density of 1.32–1.34 g/cm^3^, however, large proportions of HAV were also frequently found at higher densities, including 1.36–1.37, 1.40–1.42, and 1.45–1.48 g/cm^3^. These findings are consistent with the notion that HAV may be a parvovirus.

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