Differences between sites of binding to
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Michael J. McLean; Ahsana Dar; Michael J. Waring
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Article
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1989
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John Wiley and Sons
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English
⚖ 861 KB
The sequence specificity of bleomycin A5 and of its light-activated cobalt complex were compared by examining the relative cleavage of each strand of two DNA fragments by either species. Significant differences between the two metallobleomycins were observed. The iron-bleomycin (Fe-BLM) complex clea