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MULTINOMIAL PHASE II CANCER TRIALS INCORPORATING RESPONSE AND EARLY PROGRESSION

✍ Scribed by Zee, Benny; Melnychuk, David; Dancey, Janet; Eisenhauer, Elizabeth


Book ID
126572655
Publisher
Taylor and Francis Group
Year
1999
Tongue
English
Weight
143 KB
Volume
9
Category
Article
ISSN
1054-3406

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## Abstract ## BACKGROUND. A Phase II trial of irinotecan and cisplatin (IP) with early concurrent radiotherapy was performed in limited‐disease small‐cell lung cancer (LD‐SCLC) to evaluate the efficacy and toxicity. ## METHODS. For untreated LD‐SCLC patients, irinotecan (60 mg/m^2^, Days 1, 8,