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Multilamellar Liposomes and Solid-Supported Lipid Membranes (TRANSIL): Screening of Lipid-Water Partitioning Toward a High-Throughput Scale

✍ Scribed by Angelika Loidl-Stahlhofen; Thorsten Hartmann; Matthias Schöttner; Cornelia Röhring; Hanna Brodowsky; Johannes Schmitt; Jörg Keldenich

Book ID
110321234
Publisher
Springer US
Year
2001
Tongue
English
Weight
245 KB
Volume
18
Category
Article
ISSN
0724-8741

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✍ Angelika Loidl-Stahlhofen; Annett Eckert; Thorsten Hartmann; Matthias Schöttner 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 189 KB 👁 2 views

Quantification of membrane affinity is an important early screening step in modern drug design. However, current approaches using different lipid membrane models usually are time-consuming or show severe experimental drawbacks. In this paper we describe the use of solid-supported lipid membranes (TR