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Multifunctional silica nanoparticles with potentials of imaging and gene delivery

✍ Scribed by Gajadhar Bhakta; Rakesh Kumar Sharma; Nikesh Gupta; Simon Cool; Victor Nurcombe; Amarnath Maitra

Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
1004 KB
Volume
7
Category
Article
ISSN
1549-9634

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✦ Synopsis

From the clinical editor:

This article reports the method of preparation of gadolinium oxide-doped silica nanoparticles (nps) whose surface has been functionalized to anchor dna. these nps are paramagnetic with in vitro transfection efficiencies in cos-7 and 293t cells of about 75% and 77% compared to 'polyfect®' as positive control.

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