Multifunctional Polymeric Micelles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems
✍ Scribed by Ai, Hua; Khemtong, Chalermchai; Guthi, Jagadeesh Setti; Chin, Shook-Fong; Sherry, A. Dean; Boothman, David A.; Gao, Jinming; Nasongkla, Norased; Bey, Erik; Ren, Jimin
- Book ID
- 111984588
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 288 KB
- Volume
- 6
- Category
- Article
- ISSN
- 1530-6984
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## Abstract Multifunctional micelles for cancer cell targeting, distribution imaging, and anticancer drug delivery were prepared from an environmentally‐sensitive graft copolymer, poly(__N__‐isopropyl acrylamide‐__co__‐methacryl acid)‐__g__‐poly(D,L‐lactide) (P(NIPAAm‐__co__‐MAAc)‐__g__‐PLA), a dib
## Abstract A novel amphiphilic biodegradable graft copolymer based on poly(aspartic acid) (PASP) was prepared by coupling monomethoxy poly(ethylene glycol) as the hydrophilic segment with PASP‐__g__‐octadecyl (PASP‐__g__‐OD) as the hydrophobic backbone. The critical micelle concentration of the co