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Multifunctional Poly(2-oxazoline) Nanoparticles for Biological Applications

✍ Scribed by Kristian Kempe; Antje Vollrath; Hendrik W. Schaefer; Tobias G. Poehlmann; Christoph Biskup; Richard Hoogenboom; Stephanie Hornig; Ulrich S. Schubert

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
329 KB
Volume
31
Category
Article
ISSN
1022-1336

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✦ Synopsis

Abstract

New multifunctional copoly(2‐oxazoline) nanoparticles were prepared for cell studies. The polymer contains double‐bond side chains as potential reaction sites for “thio”‐click reactions as well as a fluorescein label covalently bound to the polymer backbone. Using the nanoprecipitation technique, spherical nanoparticles of 200–800 nm were obtained. Confocal laser scanning microscopy measurements revealed the cellular uptake of the nanoparticles.
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