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Multifunctional Nanoparticles for Drug Delivery Applications: Imaging, Targeting, and Delivery

✍ Scribed by Robert K. Prud’homme, Sonke Svenson (auth.), Sonke Svenson, Robert K. Prud'homme (eds.)


Publisher
Springer-Verlag New York
Year
2012
Tongue
English
Leaves
365
Series
Nanostructure Science and Technology
Edition
1
Category
Library

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✦ Synopsis


This book clearly demonstrates the progression of nanoparticle therapeutics from basic research to applications. This book, unlike others covering nanoparticles used in medical applications, presents the medical challenges that can be reduced or even overcome by recent advances in nanoscale drug delivery. Each chapter highlights recent progress in the design and engineering of select multifunctional nanoparticles with topics covering targeting, imaging, delivery, diagnostics, and therapy.

✦ Table of Contents


Front Matter....Pages i-x
Introduction: Benefits and Challenges for Multifunctional Nanoparticles in Medicine....Pages 1-5
Front Matter....Pages 7-7
Nanoparticles for Targeted and Temporally Controlled Drug Delivery....Pages 9-29
Development and Application of Anticancer Nanomedicine....Pages 31-46
Macrophage-Targeted Nanoparticle Delivery Systems....Pages 47-83
Paclitaxel-Triazine Dendrimer Constructs: Efficacy, Toxicity, and Characterization....Pages 85-100
Front Matter....Pages 101-101
Versatile Fixed-Ratio Drug Combination Delivery Using Hydrophobic Prodrug Nanoparticles....Pages 103-132
Polymeric Micelles for Multiple-Drug Delivery....Pages 133-152
Front Matter....Pages 153-153
Multifunctional Nanoparticles for Target-Specific Imaging and Therapy....Pages 155-171
Polymer-Modified Nanoparticles as Targeted MR Imaging Agents....Pages 173-198
Front Matter....Pages 199-199
Injectable Multistage Nanovectors for Enhancing Imaging Contrast and Directed Therapy....Pages 201-223
Targeted, Multifunctional Hydrogel Nanoparticles for Imaging and Treatment of Cancer....Pages 225-255
Theranostic Polymeric Micelles for Cancer Imaging and Therapy....Pages 257-276
Multifunctional Nanoparticles for Personalized Medicine....Pages 277-293
Dendrimer-Based Nanoparticle Therapies: Can Uniform Multifunctional Therapeutics Be Made with Current Chemical Approaches?....Pages 295-313
Multivalent Dendritic Architectures for Theranostics....Pages 315-344
Design and Engineering of Multifunctional Quantum Dot-Based Nanoparticles for Simultaneous Therapeutic-Diagnostic Applications....Pages 345-365
Back Matter....Pages 367-373

✦ Subjects


Nanotechnology and Microengineering; Pharmacology/Toxicology; Organic Chemistry; Spectroscopy/Spectrometry; Immunology


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