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Multifunctional CD4+T cells in patients with American cutaneous leishmaniasis

✍ Scribed by A. B. B. Macedo; J. C. Sánchez-Arcila; A. O. Schubach; S. C. F. Mendonça; A. Marins-Dos-Santos; M. de Fatima Madeira; T. Gagini; M. I. F. Pimentel; P. M. De Luca

Book ID
108701539
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
295 KB
Volume
167
Category
Article
ISSN
0009-9104

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## Abstract Th1 CD4^+^ T cells and their derived cytokines are crucial for protection against __Mycobacterium tuberculosis__. Using multiparametric flow cytometry, we have evaluated the distribution of seven distinct functional states (IFN‐γ/IL‐2/TNF‐α triple expressors, IFN‐γ/IL‐2, IFN‐γ/TNF‐α or