Multidrug-Resistant Phenotype Influences the Differentiation of a Human Colon Carcinoma Cell Line
β Scribed by Odile Rimet; Aline Mirrione; Yves Barra
- Book ID
- 115583816
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 378 KB
- Volume
- 259
- Category
- Article
- ISSN
- 0006-291X
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π SIMILAR VOLUMES
In addition to P-glycoprotein (Pgp), 2 proteins related to multidrug resistance (MDR) have recently been described. The Multidrug-Resistance-associated protein (MRP) is one of the ATP-binding-cassette (ABC) transporters. The Lung-Resistance Protein (LRP) is the major component of human vaults, which
## Abstract Amooranin (AMR), a plant terpenoid, isolated from __Amoora rohituka__, was investigated for its ability to overcome multidrug resistance in human leukemia and colon carcinoma cell lines. AMR IC~50~ values of multidrugβresistant leukemia (CEM/VLB) and colon carcinoma (SW620/Adβ300) cell