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Multidrug resistance-associated proteins and implications in drug development

✍ Scribed by Ya-He Liu; Yuan-Ming Di; Zhi-Wei Zhou; Sui-Lin Mo; Shu-Feng Zhou

Book ID
108940569
Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
160 KB
Volume
37
Category
Article
ISSN
0305-1870

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## Abstract Overexpression of the P‐glycoprotein/multidrug resistance 1 __(MDR1)__ and multidrug resistance protein 1 __(MRP1)__ gene is closely associated with the clinical outcome of various malignancies, and it is involved in responses to some anticancer chemotherapeutic agents including doxorub