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Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis

✍ Scribed by Karin Dilger; Ingolf Cascorbi; Frank Grünhage; Simon Hohenester; Tilman Sauerbruch; Ulrich Beuers

Book ID
111237462
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
132 KB
Volume
26
Category
Article
ISSN
0106-9543

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✍ Annarosa Floreani; Isabella Carderi; Angela Variola; Erik Rosa Rizzotto; James N 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 237 KB

A single nucleotide polymorphism characterized by the substitution of valine for glutamate (V1188E) in exon 25 of the multidrug resistance protein 2 gene was found in a group of patients with primary biliary cirrhosis. This heterozygous mutation was significantly associated with the presence of prur