Multicomponent Reactions: Synthesis of Bioactive Heterocycles

✍ Scribed by K.L. Ameta Ph.D., Anshu Dandia

Publisher: CRC Press
Year: 2017
Tongue: English
Leaves: 409
Edition: 1
Category: Library

No coin nor oath required. For personal study only.

✦ Synopsis

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential

✦ Table of Contents

Content: MCR for carbon-carbon and carbon-heteroatom coupling reactions. MCR for cycloadditions, and other related reactions. MCR as promising tool for the synthesis of bioactive heterocycles: Pyrazole.MCR as promising tool for the synthesis of bioactive heterocycles: Imidazole. MCR as promising tool for the synthesis of bioactive heterocycles: Isoxazole. MCR as promising tool for the synthesis of bioactive heterocycles: Oxazole. MCR as promising tool for the synthesis of bioactive heterocycles: Thiazole. MCR as promising tool for the synthesis of bioactive heterocycles: Isothiazole. MCR as promising tool for the synthesis of bioactive heterocycles: Benzimidazole. MCR as promising tool for the synthesis of bioactive heterocycles: Sulfathiazole.

✦ Subjects

Heterogeneous catalysis.;Heterocyclic compounds -- Synthesis.;Bioactive compounds.;Heterocyclic compounds.;SCIENCE / Chemistry / Organic

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