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Multicomponent pharmaceutical cocrystals: furosemide and pentoxifylline

✍ Scribed by Stepanovs, Dmitrijs; Mishnev, Anatoly


Book ID
118123657
Publisher
International Union of Crystallography
Year
2012
Tongue
English
Weight
767 KB
Volume
68
Category
Article
ISSN
0108-2701

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Furosemide was screened in cocrystallization experiments with pharmaceutically acceptable coformer molecules to discover cocrystals of improved physicochemical properties, that is high solubility and good stability. Eight novel equimolar cocrystals of furosemide were obtained by liquid-assisted grin