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Multicomponent Approach Towards the Synthesis of Substituted Pyrroles under Supramolecular Catalysis Using β-Cyclodextrin as a Catalyst in Water Under Neutral Conditions

✍ Scribed by Sabbavarapu Narayana Murthy; Bandaru Madhav; Akkiligunta Vijay Kumar; Kakulapati Rama Rao; Yadavalli Venkata Durga Nageswar

Book ID: 102253681
Publisher: John Wiley and Sons
Year: 2009
Tongue: German
Weight: 175 KB
Volume: 92
Category: Article
ISSN: 0018-019X
DOI: 10.1002/hlca.200900098

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✦ Synopsis

Abstract

Synthesis of substituted pyrroles in H~2~O by using β‐cyclodextrin as a supramolecular catalyst is described. This reaction has several advantages over existing methods and provides substituted pyrroles in good‐to‐excellent yields (79–89%). The supramolecular catalysis of the reaction was studied using ^1^H‐NMR spectroscopy. β‐Cyclodextrin can be recovered and reused several times without loss of activity.

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