Multicompartmental Micro- and Nanocapsules: Hierarchy and Applications in Biosciences
✍ Scribed by Mihaela Delcea; Alexey Yashchenok; Kristina Videnova; Oliver Kreft; Helmuth Möhwald; Andre G. Skirtach
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 701 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1616-5187
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Multicompartmentalized micro‐ and nanocapsules allow simultaneous delivery of several vectors or biomolecules; they are the next generation of carriers with increased complexity. Here we overview multicompartment micro‐ and nanocapsules and present a road‐map for future developments in the field. Four basic building block structures are demonstrated, three isotropic: concentric, pericentric, and innercentric, and one anisotropic: acentric. As an elaborate implementation of multicompartmentalization, an enzyme‐catalyzed reaction inside the same capsule carrying both an enzyme and a substrate is shown. Applications of multicompartmentalized microcapsules for simultaneous multiple drug delivery in bio‐medicine are discussed.
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