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Multicompartmental Analysis of [11C]-Carfentanil Binding to Opiate Receptors in Humans Measured by Positron Emission Tomography

✍ Scribed by Frost, J. J.; Douglass, K. H.; Mayberg, H. S.; Dannals, R. F.; Links, J. M.; Wilson, A. A.; Ravert, H. T.; Crozier, William C.; Wagner, H. N.


Book ID
109870139
Publisher
Nature Publishing Group
Year
1989
Tongue
English
Weight
489 KB
Volume
9
Category
Article
ISSN
0271-678X

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By means of positron emission tomography the uptake and kinetics of N-(methyl-11C)clozapine in different brain regions have been studied in Rhesus monkeys. 11C-clozapine rapidly entered the brain and maximum radioactive uptake was seen 5-12 min after administration. Highest uptake was measured in th