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Multicentre prospective phase II trial of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor mutations: results of the West Japan Thoracic Oncology Group trial (WJTOG0403)

โœ Scribed by Tamura, K; Okamoto, I; Kashii, T; Negoro, S; Hirashima, T; Kudoh, S; Ichinose, Y; Ebi, N; Shibata, K; Nishimura, T


Book ID
109999424
Publisher
Nature Publishing Group
Year
2008
Tongue
English
Weight
142 KB
Volume
98
Category
Article
ISSN
0007-0920

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โœ Tetsuya Mitsudomi; Satoshi Morita; Yasushi Yatabe; Shunichi Negoro; Isamu Okamot ๐Ÿ“‚ Article ๐Ÿ“… 2010 ๐Ÿ› The Lancet ๐ŸŒ English โš– 239 KB

Background Patients with non-small-cell lung cancer harbouring mutations in the epidermal growth factor receptor (EGFR) gene respond well to the EGFR-specific tyrosine kinase inhibitor gefitinib. However, whether gefitinib is better than standard platinum doublet chemotherapy in patients selected by