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Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma

✍ Scribed by M. Bower; E. S. Newlands; N. M. Bleehen; M. Brada; R. J. H. Begent; H. Calvert; I. Colquhoun; P. Lewis; M. H. Brampton


Publisher
Springer
Year
1997
Tongue
English
Weight
139 KB
Volume
40
Category
Article
ISSN
0344-5704

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## Abstract ## BACKGROUND. The prognosis for patients with recurrent high‐grade gliomas is poor and treatment options are limited. Current chemotherapeutic regimens can improve clinical outcomes, but extend survival by only a few months. Temozolomide is a methylating agent that is typically admini