Multicentre comparative clinical study of a new wound dressing: PA286 (Inerpan)

✍ Scribed by J. Guilbaud; C. Honde

• Book ID: 104659149
• Publisher: Springer
• Year: 1993
• Tongue: English
• Weight: 387 KB
• Volume: 16
• Category: Article
• ISSN: 1435-0130
• DOI: 10.1007/bf00196436

✦ Synopsis

10 French burn centres participated in a prospective, randomised clinical trial comparing a new wound dressing, PA286 (trademark Inerpan) 1 with the dressings commonly used in each centre, such as vaseline gauze, vaseline gauze with antibiotics, silver sulphadiazine cream and polyurethane film. A total of 460 patients with second degree burns, skin donor sites, meshed skin grafts and losses of skin substance were included in the study. Each patient acted as his, or her, own control. Two similar lesions in terms of site, depth and surface area were compared, one being treated with Inerpan, the other one with a control dressing. The following parameters were studied: healing time, intensity of pain, local safety, and frequency of dressing changes. Analysis of the results showed that healing time and importance of local events such as exudate and suppuration did not differ significantly. Intensity of pain experienced by the patient and frequency of dressing renewals were significantly lower with Inerpan then with control dressings.