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Multicenter phase II trial of first-line irinotecan (CPT-11) and gemcitabine (GMB) in patients with unresectable pancreatic cancer

✍ Scribed by Stathopoulos, G.; Rigatos, S.; Androulakis, N.; Souglakos, J.; Kouroussis, Ch.; Dimopoulos, A.M.; Aravantinos, G.; Giannakakis, Th.; Foutzilas, G.; Stathopoulos, J.; Georgoulias, V.


Book ID
122878589
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
198 KB
Volume
37
Category
Article
ISSN
0959-8049

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## Background: This multicenter, phase ii trial was performed to evaluate the antitumor activity and toxicity of irinotecan (cpt-11) in patients with metastatic colorectal carcinoma that had recurred or progressed after 5-fluorouracil (5-fu)-based chemotherapy. ## Methods: Cpt-11 was given as a 9