𝔖 Bobbio Scriptorium
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Multibranched peptide constructs derived from the V3 loop of envelope glycoprotein gp120 inhibit human immunodeficiency virus type 1 infection through interaction with CD4

✍ Scribed by Abdelaziz Benjouad; Françcoise Chapuis; Emmanuel Fenouillet; Jean-Claude Gluckman


Book ID
114093657
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
774 KB
Volume
206
Category
Article
ISSN
0042-6822

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The envelope glycoprotein (gpl20) of HIV-1 was labeled with fluorescein by using 6- [4,6-dichlorotriazinyl]aminofluorescein. The labeled glycoprotein was found to bind to CD4-positive CEM cells. Monoclonal antibody OKT4a but not OKT4 blocked this binding. Similar specific binding of fluorescein-labe