Multi-parameter battery state estimator based on the adaptive and direct solution of the governing differential equations

On the accuracy of estimation of basic p

On the accuracy of estimation of basic pharmacokinetic parameters by the traditional noncompartmental equations and the prediction of the steady-state volume of distribution in obese patients based upon data derived from normal subjects

✍ Leonid M. Berezhkovskiy 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 339 KB 👁 1 views

The steady-state and terminal volumes of distribution, as well as the mean residence time of drug in the body (V ss , V $ , and MRT) are the common pharmacokinetic parameters calculated using the drug plasma concentration-time profile C p (t) following intravenous (i.v. bolus or constant rate infusi