Multi-institutional randomized clinical trials as a research method in cancer
β Scribed by Hernando G. Ortiz
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 536 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0360-3016
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## Abstract Reasons for patient nonβentry in randomized clinical trials (RCTs) assessing oncologic treatment modalities are not well documented in the literature. We have prospectively recorded reasons for RCT nonβentry in breast cancer patients at St. Michael's Hospital, Toronto. From September 19
In randomized clinical trials comparing treatment effects on diseases such as cancer, a multi-centre trial is usually conducted to accrue the required number of patients in a reasonable period of time. While we interpret the average treatment effect, it is necessary to examine the homogeneity of the