Multi-element analysis of biological tissues by inductively coupled plasma mass spectrometry: healthy sprague dawley rats

✍ Scribed by Yves Gélinas; Massayon Youla; Richard Béliveau; Jean-Pierre Schmit; Jocelyne Ferraris

• Publisher: Elsevier Science
• Year: 1992
• Tongue: English
• Weight: 711 KB
• Volume: 269
• Category: Article
• ISSN: 0003-2670
• DOI: 10.1016/0003-2670(92)85140-2

✦ Synopsis

The normal morgamc contents of bone, brain, exythrocyte, heart, kidney cortex, ludney medulla, hver, lung, muscle and plasma from healthy Sprague Dawley rats were estabhshed by using a general method developed for mductwely coupled plasma mass spectrometrlc multi-element determmatlons of most of the elements present m blologlcal tissues The most characterlstlc elemental pattern of each tissue was ldentlfled via a statIstIca multwarlate analysis and a pnnclpal component analysis helped to elucidate the correlations between elements and tissues Keywords Inductwely coupled plasma-mass spectrometry, Blologlcal samples, Rats, Trace elements Correspondence to Y GChnas, Uruversit6 du QuCbec ?I Mon-using dlstmct techmques and a wide iarlety of t&al, Dhpartement de Chrmle and GEOTOP, BP 8888, instruments This situation mainly results from Succursale A, Montrhal, Qutbec H3C 3P8 (Canada) the lack of a single techmque capable to perform